What Is MRONJ?

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious complication that can damage jawbone. It occur after treatments like pulling tooth or treating severe gum disease. affects some people who are taking have taken medications to protect bones. These medications, bisphosphonates, may be used at high doses help manage bone cancer other types spread bone. They also prescribed severely weakened bones from conditions osteogenesis imperfecta. Much lower osteoporosis. In these MRONJ keep healing properly procedures affect bone, especially extraction 1 more teeth. cause loss pain, infection, loose teeth, and exposed Researchers estimate 10 100 with develop MRONJ.1American Dental AssociationOncology agents medication-related jaw. 2019.https://www.ada.org/en/member-center/oral-health-topics/oncology-agents-and-medication-related-osteonecrosis-of-the-jawGoogle Scholar For those for osteoporosis this number drops in 10,000.2American AssociationOsteoporosis 2019.https://www.ada.org/en/member-center/oral-health-topics/osteoporosis-medicationsGoogle Other factors increase risk developing include3American AssociationThe ADA Practical Guide Patients With Medical Conditions. John Wiley & Sons, 2016Google ▪being older than 65 years▪periodontitis▪smoking▪ill-fitting dentures▪diabetes Symptoms include4Otto S. Pautke C. Van den Wyngaert T. Niepel D. Schiødt M. jaw: prevention, diagnosis management patients metastases.Cancer Treat Rev. 2018; 69: 177-187Abstract Full Text PDF PubMed Scopus (94) Google ▪pain, swelling, infection gums jaw▪loose teeth▪numbness feeling heaviness jaw▪gums do not heal does tissue protecting it When you facing cancer, seeing dentist might seem important,5Ruggiero S.L. Dodson T.B. Fantasia J. et al.American Association Oral Maxillofacial Surgeons. American Surgeons position paper on 2014 update.J Maxillofac Surg. 2014; 72: 1938-1956Abstract (1323) complete dental examination could identify disease should treated before start strength. Give your health history, including any taken, taking, near future. If being osteoporosis, consider all risks involved. Although carries small MRONJ, breaking due much higher. addition dentist, good care home important:▪brush teeth twice day fluoride toothpaste▪clean between daily▪eat healthy diet low sugar condition involve bone-strengthening medications. Keeping up daily regular visits limit need MRONJ.